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Parkinson's Disease

What is Parkinson’s disease?

Parkinson’s is a progressive brain disorder that leads to shaking, stiffness, and difficulty with walking, balance, and coordination. In Parkinson’s disease, neurons in your brain gradually break down and die. Since neurons produce a chemical called dopamine, Parkinson’s is characterized by low dopamine levels, causing many of the symptoms associated with Parkinson’s.


How common is Parkinson’s disease?

It’s been thought that about 1 in every 500 people will develop it in their lifetime.


Who is most at risk for Parkinson’s disease?

Most people who develop Parkinson’s are over 50, so age is definitely a significant factor. Men are more likely to obtain Parkinson’s disease than women.


Several other factors play in role in determining your chance of getting Parkinson’s, including hereditary genes and exposure to toxins.


What are the symptoms of Parkinson’s disease?

Symptoms of Parkinson’s disease are different for everyone. Usually, the symptoms of Parkinson’s are more severe on one side of the body, even if they affect both sides. The most common symptoms of Parkinson’s disease are:

  • Tremors (usually starts in your limbs, then moves to your fingers)

  • Slowed movement (bradykinesia)

  • Rigid muscles

  • Impaired posture and balance

  • Loss of automatic movements, including blinking, smiling and moving your arms when walking

  • Speech changes (your voice can become more monotonous, quick, soft, slurred, and hesitant)

  • Writing changes


What additional problems arise from Parkinson’s disease?

Because the brain is mentally impaired, the whole body is thoroughly affected by Parkinson’s. Some additional problems that may arise include:

  • Thinking difficulties, which can turn into dementia

  • Depression and emotional changes, such as fear, anxiety, or loss of motivation

  • Swallowing problems and drooling

  • Chewing and eating problems

  • Sleep problems and sleep disorders, including insomnia and rapid eye movement

  • Bladder problems

  • Constipation

  • Blood pressure changes

  • Smell dysfunction

  • Fatigue

  • Pain throughout the body

  • Sexual dysfunction


How is Parkinson’s disease diagnosed?

In most cases, doctors will determine whether a person has Parkinson’s by noting a person’s symptoms. However, some supplemental tests may be used to supplement a doctor’s diagnosis, including:

  • Dopamine transporter scan (DaTscan)

  • Blood tests - to rule out other diseases/conditions

  • Imaging tests, such as PET and MRI scans - to rule out other neurological conditions


How is Parkinson’s disease treated?

Unfortunately, there is no cure for Parkinson’s. However, many treatments can help control symptoms. Here are the various therapies used for Parkinson’s:


Medications/Procedures:

  • Carbidopa-levodopa - the most effective medication, is a natural chemical that converts to dopamine in the brain

  • Dopamine agonists - mimics dopamine effects in your brain

  • MAO B inhibitors - inhibits an enzyme that breaks down dopamine

  • Anticholinergics/Amantadine - helps control tremors

  • Deep brain stimulation - may reduce tremors, reduce rigidity, and improve slowing of movement,


Lifestyle Changes:

  • Healthy diets - diets high in fiber and fluids can reduce constipation associated with Parkinson’s

  • Exercise - increases muscle strength, flexibility, balance, reduces depression/anxiety

  • Avoiding falls by distributing weight evenly on both feet, not carrying things while walking, and not walking backward


Alternative Medicine:

  • Massage - reduce muscle tension and promote relaxation

  • Tai chi - improves flexibility, balance, and muscle strength

  • Yoga - increase flexibility and balance

  • Meditation - reduces stress and pain, improve well-being


How to prevent Parkinson’s disease?

It isn’t possible to prevent Parkinson’s, but healthy habits can help reduce the risk of getting it. Some of these habits include consuming turmeric and flavonoids, which are both full of antioxidants, and avoiding reheated oils and toxins.


Sources:

https://www.nia.nih.gov/health/parkinsons-disease#:~:text=Parkinson's%20disease%20is%20a%20brain,have%20difficulty%20walking%20and%20talking.

https://www.nhs.uk/conditions/parkinsons-disease/#:~:text=It's%20thought%20around%201%20in,get%20Parkinson's%20disease%20than%20women.

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